Imagine the two shapes above are pictures you want to layer up or down
(pyrimage invertage or similar)
First you cut the two pictures idetically with the largest die.
Then you alternate the sizes on each one as shown.
You're then left with cutouts as above and you have a larger piece like a frame which you disgard.
When you layer them up the holes are hidden.
Just make sure the last one has enough pads beneath it all the way down.
If you don't have a picture to do this to but have some pretty coloured card you can glue them flat like this and put them through the big shot etc with an embossing folder.
The above result had it's edges coloured with cats eye chalk before I glued it together.